Reduction with Tritides

Specific tritiation reagents may be required for the synthesis of complex organic molecules with numerous functional groups. These should be regioselective and have a high specific activity. The figure below shows the wide variety of different tritide reagents. All tritides are derived from lithium tritide (LiT). In order to achieve the highest possible specific activity and the best possible quality, the tritide reagent is prepared immediately before use. 

We produce sodium borohydride from sodium borohydride in a specially developed plant for thermal H/T exchange. The product is available from our catalogue. The reagent has a specific activity of 80 Ci/mmol and is supplied as a solid in sealed ampoules in an argon atmosphere. Sodium boron tritide is a versatile reagent that can be used in both reductions and gas-free dehalogenations. Many other reagents can be derived from NaBT4, such as sodium triacetoxybortritide, which can be used as a selective reducing agent in reductive aminations.