MethylationA Useful Tool to Achieve High Specific Activity
As shown in the scheme below, [H-3]-methylation has a very broad field of application. There are several methylation reagents known in organic chemistry. The most applied is methyl iodide, a strong and reliable methylation reagent. These reactions are examples, and more possibilities are known for the introduction of the methyl group (-CT3) with its high specific activity (>75 Ci/mmol, equal to >2.78 TBq/mmol). Please note that we always freshly prepare [H-3]-methyl iodide in order to ensure the best quality of the product.